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DC Field | Value | Language |
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dc.contributor.author | Prasad, Ashish | - |
dc.contributor.author | Muthamilarasan, Mehanathan | - |
dc.contributor.author | Prasad, Manoj | - |
dc.date.accessioned | 2020-06-22T09:34:25Z | - |
dc.date.available | 2020-06-22T09:34:25Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Plant Cell Reports, 39(9): 1109-1114 | en_US |
dc.identifier.issn | 1432-203X | - |
dc.identifier.other | https://doi.org/10.1007/s00299-020-02560-w | - |
dc.identifier.uri | https://link.springer.com/article/10.1007/s00299-020-02560-w | - |
dc.identifier.uri | http://223.31.159.10:8080/jspui/handle/123456789/1069 | - |
dc.description | Accepted date: 12 June 2020 | en_US |
dc.description.abstract | The exponential spread of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emphasizes the immediate need for efective antiviral drugs and vaccines that could control and prevent the spread of this pandemic. Several new and repurposed drugs are being tested for their efectiveness in the treatment regime, and the development of vaccines is underway. The availability of genome sequence information of the virus and the identifcation of potential targets to neutralize and eradicate the infection have enabled the search for novel as well as existing molecules to perform the desired function. However, the application of plants in the development of potential biomolecules, such as antibiotics and vaccines, is limited. Traditional medicines involving plant-based formulations have proven successful in boosting immunity and providing tolerance to virus infections. Still, in-depth studies are not available to explore the bioactive compounds of plant origin and their mechanism of action. Given this, the current opinion article conveys our thoughts and perspectives on the promising usage of plant-based biomolecules in circumventing SARS-CoV-2, and how these molecules can work synergistically with other potential drugs for treating SARS-CoV-2. | en_US |
dc.description.sponsorship | Authors’ work in this area is supported by J.C. Bose National Fellowship Grant of Department of Science and Technology, Government of India (File no.: JCB/2018/000001). A.P. acknowledges the Council for Scientifc and Industrial Research, Govt. of India for research fellowship. Authors are thankful to DBT-eLibrary Consortium (DeLCON) for providing access to e-resources. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Nature Publishing AG | en_US |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | Plant-based drugs | en_US |
dc.subject | Antiviral biomolecules | en_US |
dc.subject | Plant-based vaccines | en_US |
dc.subject | Traditional medicine | en_US |
dc.subject | Synergistic effect | en_US |
dc.subject | covid19 | en_US |
dc.title | Synergistic antiviral effects against SARS-CoV-2 by plant-based molecules | en_US |
dc.type | Article | en_US |
Appears in Collections: | Institutional Publications |
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