Please use this identifier to cite or link to this item: http://223.31.159.10:8080/jspui/handle/123456789/1287
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dc.contributor.authorSharma, Namisha-
dc.contributor.authorPrasad, Ashish-
dc.contributor.authorPrasad, Manoj-
dc.date.accessioned2022-01-11T07:34:18Z-
dc.date.available2022-01-11T07:34:18Z-
dc.date.issued2022-
dc.identifier.citationJournal of Virology, 96(5): e0208421en_US
dc.identifier.issn0022-538X-
dc.identifier.issn1098-5514-
dc.identifier.otherhttps://doi.org/10.1128/jvi.02084-21-
dc.identifier.urihttps://journals.asm.org/doi/10.1128/jvi.02084-21?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&-
dc.identifier.urihttp://223.31.159.10:8080/jspui/handle/123456789/1287-
dc.descriptionAccepted date: 5 January 2022en_US
dc.description.abstractThe Sw5 gene cluster furnishes robust resistance to Tomato spotted wilt virus in tomato, which has led to its widespread applicability in agriculture. Among the five orthologs, Sw5b functions as a resistance gene against a broad-spectrum Tospovirus and is linked with Tospovirus resistance. However, its paralog, Sw5a, has been recently implicated in providing resistance against Tomato leaf curl New Delhi virus, broadening the relevance of the Sw5 gene cluster in promoting defense against plant viruses. We propose that plants have established modifications within the homologs of R genes that permit identification of different effector proteins and provide broad and robust resistance against different pathogens through activation of hypersensitive response and cell death.en_US
dc.description.sponsorshipThe work of the authors on plant-virus interaction is supported by funding from Ministry of Science and Technology, Government of India (National Institute of Plant Genome Research core grant and JC Bose Fellowship JCB/2018/000001) to M.P. N.S. acknowledges the Women Excellence Award from Science and Engineering Research Board, Department of Science and Technology, Government of India (WEA/2020/000004). We thank the DBT eLibrary Consortium (DeLCON) for providing access to e-resources. The authors have no conflict of interests.en_US
dc.language.isoen_USen_US
dc.publisherAmerican Society for Microbiologyen_US
dc.subjectSw5 geneen_US
dc.subjecttomato spotted wilt virusen_US
dc.subjecttomato leaf curl virusen_US
dc.subjecthypersensitive responseen_US
dc.subjectR gene-mediated resistanceen_US
dc.titleRole of Sw5 gene cluster in the fight against plant virusesen_US
dc.typeArticleen_US
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