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DC Field | Value | Language |
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dc.contributor.author | Prasad, Ashish | - |
dc.contributor.author | Sharma, Shambhavi | - |
dc.contributor.author | Prasad, Manoj | - |
dc.date.accessioned | 2023-09-22T10:21:42Z | - |
dc.date.available | 2023-09-22T10:21:42Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms, 1866(4): 194983 | en_US |
dc.identifier.issn | 1876-4320 | - |
dc.identifier.issn | 1874-9399 | - |
dc.identifier.other | https://doi.org/10.1016/j.bbagrm.2023.194983 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S1874939923000780?via%3Dihub | - |
dc.identifier.uri | http://223.31.159.10:8080/jspui/handle/123456789/1522 | - |
dc.description | Accepted date: 12 September 2023 | en_US |
dc.description.abstract | Plant-virus interaction is a complex phenomenon and involves the communication between plant and viral factors. Viruses have very limited coding ability yet, they are able to cause infection which results in huge agro-economic losses throughout the globe each year. Post-translational modifications (PTMs) are covalent modifications of proteins that have a drastic effect on their conformation, stability and function. Like the host proteins, geminiviral proteins are also subject to PTMs and these modifications greatly expand the diversity of their functions. Additionally, these viral proteins can also interact with the components of PTM pathways and modulate them. Several studies have highlighted the importance of PTMs such as phosphorylation, ubiquitination, SUMOylation, myristoylation, S-acylation, acetylation and methylation in plant-geminivirus interaction. PTMs also regulate epigenetic modifications during geminivirus infection which determines viral gene expression. In this review, we have summarized the role of PTMs in regulating geminiviral protein function, influence of PTMs on viral gene expression and how geminiviral proteins interact with the components of PTM pathways to modulate their function. | en_US |
dc.description.sponsorship | Authors' work in the area of plant molecular genetics and genomics is supported by the JC Bose Fellowship (File No.: JCB/2018/000001) from Science and Engineering Research Board (SERB), Govt. of India, India and Core Grant of National Institute of Plant Genome Research, New Delhi, India to MP. AP acknowledges research grant from Department of Science and Technology, Govt. of India (Faculty Registration No.: IFA22- LSPA 152). SS acknowledges research fellowship from Department of Biotechnology, Govt. of India. The authors are thankful to DBT-eLibrary Consortium (DeLCON) for providing access to e-resources. Figures were created using BioRender. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Elsevier B.V. | en_US |
dc.subject | Acetylation | en_US |
dc.subject | Geminivirus | en_US |
dc.subject | Phosphorylation | en_US |
dc.subject | Post-translational modifications | en_US |
dc.subject | S-acylation | en_US |
dc.subject | Ubiquitin-like modifications | en_US |
dc.subject | Ubiquitination | en_US |
dc.title | Post translational modifications at the verge of plant-geminivirus interaction | en_US |
dc.type | Article | en_US |
Appears in Collections: | Institutional Publications |
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Prasad M_2023_11.pdf Restricted Access | 3.29 MB | Adobe PDF | View/Open Request a copy |
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