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DC Field | Value | Language |
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dc.contributor.author | Sharma, Namisha | - |
dc.contributor.author | Sahu, Pranav Pankaj | - |
dc.contributor.author | Puranik, Swati | - |
dc.contributor.author | Prasad, Manoj | - |
dc.date.accessioned | 2015-11-18T08:18:49Z | - |
dc.date.available | 2015-11-18T08:18:49Z | - |
dc.date.issued | 2013 | - |
dc.identifier.citation | Mol. Biotechnol. 55(1): 63-77 | en_US |
dc.identifier.issn | 1559-0305 | - |
dc.identifier.uri | http://172.16.0.77:8080/jspui/handle/123456789/365 | - |
dc.description.abstract | Regulation of several biological functions in plants has now been known to involve diverse RNA silencing pathways. These vital pathways involve various components such as dsRNA, Dicer, RNA-dependent RNA polymerase and Argonaute proteins, which lead to the production of several small RNAs (sRNAs) varying in their sizes. These sRNAs have significant role in the regulation of gene expression at transcriptional and translational levels. Among them, small interfering RNAs (siRNAs; majorly 21, 22 and 24 nt) have been shown to play an important role in plants' resistance against many viruses by inhibiting the viral gene expression. Furthermore, it has also been highlighted that siRNA-mediated methylation of viral DNA confers resistance to various plant DNA viruses. In this review, we have outlined the recent advances made using the siRNA-mediated antiviral strategy, along with methylation-based epigenetic defensive mechanisms as a protective measure against diverse plant viruses. | en_US |
dc.description.sponsorship | Grateful thanks are due to the Director, National Institute of Plant Genome Research (NIPGR), New Delhi, India, for providing facilities. The authors work in this area were supported by the core grant of NIPGR. Ms Namisha Sharma acknowledges the award of Junior Research Fellowship from DBT, New Delhi. We would like to thank all the reviewers for their con- structive comments. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer | en_US |
dc.subject | Plant virus | en_US |
dc.subject | Host–virus interaction | en_US |
dc.subject | Gene silencing | en_US |
dc.subject | Small RNA | en_US |
dc.subject | DNA methylation | en_US |
dc.title | Recent advances in plant-virus interaction with emphasis on small interfering RNAs (siRNAs) | en_US |
dc.type | Article | en_US |
dc.identifier.officialurl | http://link.springer.com/article/10.1007%2Fs12033-012-9615-7 | en_US |
dc.identifier.doi | 10.1007/s12033-012-9615-7 | en_US |
Appears in Collections: | Institutional Publications |
Files in This Item:
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Prasad M_2012_10.pdf Restricted Access | 501.41 kB | Adobe PDF | View/Open Request a copy |
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